Inositol | Designs for Health | 120 capsules or 100 or 250 grams

Inositol is one of the most versatile nutrients for promoting brain wellness, a positive and relaxed outlook, and restful sleep. Inositol is also one of the most crucial nutrients for promoting female hormonal health through its role in supporting optimal liver function. It also helps maintain healthy serotonin metabolism, and by so doing helps treat many conditions that involve poor serotonin function, including depression, agoraphobia, panic disorder, and obsessive compulsive disorder.

Inositol also helps prevent and treat pediatric respiratory distress syndrome. Recent studies have also looked into its pain relieving ability. Low levels of inositol occur in patients with diabetes, renal failure, and multiple sclerosis, suggesting inositol may be of benefit here as well.

Signs of inadequate inositol intake include:

• Difficulty falling asleep
• PMS, fibroid tumors, and other problems caused by female hormonal imbalance
• Depression
• Anxiety

NATURE’S SLEEPING PILL: Taking inositol naturally helps the body achieve a more relaxed state. Inositol is prized by many for its ability to promote a more restful sleep. Taken during the day, inositol can help relieve anxiety and promote a more even-tempered mood. Inositol should be taken directly before bedtime to improve sleep quality.

PROMOTING FEMALE HORMONAL HEALTH: Inositol works in partnership with phosphatidyl choline (PC) to help the liver metabolize hormones such as estrogen and progesterone. By doing so, Inositol helps alleviate PMS, fibrocystic breast disease, fibroid tumors, and a range of other health problems caused by female hormonal imbalance. Inositol and PC are must supplements for anyone taking female hormone replacement therapy.

ALLEVIATING DEPRESSION: Depressed patients have lower levels of inositol in their brain. Research shows that taking 6-12 grams of inositol per day for four weeks significantly improves mood and reduces the severity of depression. Inositol can be safely used along with antidepressant medications.

TREATING OTHER AILMENTS:6 grams per day of inositol has helped increase cognitive function in Alzheimer’s patients. The same dose has been found helpful in relieving diabetic neuropathy symptoms. Inositol may also be useful in the treatment of multiple sclerosis by promoting increased nerve conduction. Inositol may turn out to be an essential nutrient for a healthy pregnancy in humans, as animal studies have demonstrated it can prevent folic acid resistant neural tube defects. Inositol may be of particular importance in diabetic pregnancies. Inositol supplementation during pregnancy should only be done with the guidance of a health care practitioner and should not exceed 1,000 mg per day.

TAKING INOSITOL: For general health, a more restful sleep, and an overall positive outlook, start with ½ teaspoon of inositol powder per day. For promoting female hormonal balance, one teaspoon or more per day is helpful. For relieving depression, anxiety, agoraphobia, OCD and panic attacks, 1-4 teaspoons should be used. Inositol powder has a naturally sweet, pleasant taste and mixes easily in water.

Benefits of Inositol:

• Has a relaxing effect which promotes a more restful sleep
• Works in the liver along with phosphatidyl choline to help relieve female hormonal problems such as PMS, fibroid tumors and fibrocystic breast disease
• Useful in the treatment of depression, agoraphobia, panic disorder and obsessive compulsive disorder
• Helpful in alleviating the symptoms of diabetic neuropathy
• May be essential for a healthy pregnancy, especially in diabetic mothers
• Promotes retinal and lung health
• May be useful in the treatment of Alzheimer’s Disease

Insomnitol by Designs for Health Categories:

• B Vitamin Formulas
• Sleep Support
• Brain Wellness Support
• Endocrine Support
• Stress Management

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Serving Size: 1 capsule.

Recommended Use: As a dietary supplement, take one or more capsules per day or as directed by your health care practitioner.

Serving Size: 1/4 teaspoon.

Recommended Use: As a dietary supplement, take one-quarter to one teaspoon per day or as directed by your health care practitioner.

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Metabolic Synergy™ | Designs for Health | 180 capsules

Metabolic Synergy by Designs for Health is an ideal formula for the metabolic syndrome individual. It includes two more state of the art, newly researched anti-glycating agents carnosine and benfothiamine (a form of vitamin B1) for preventing diabetic complications. The mineral forms of magnesium, chromium, zinc, manganese and vanadium are true chelates from Albion, the leader in the manufacturer of mineral chelates with superior absorption.

A few core nutrients have been added to make Metabolic Synergy™ a complete multivitamin mineral. This multivitamin was originally designed by a diabetes specialist, Dr. Ron Rosedale, and was updated with the help of Dr. Bob Steinberg. Do You Know what your blood sugar levels should be? For people without diabetes, according to experts, blood sugar levels should be between 70 and 120 mg/ dL. For people with type 2 diabetes: Fasting (not eating for a period of time): up to 130 mg/dL and After meals: less than 180 mg/dL.

Metabolic Synergy™ by Designs for Health may help:

• Support conversion of carbohydrates to energy
• Lower fasting and average glucose levels (hemoglobin A1C)
• Lower fasting and average insulin and leptin levels with improved tissue sensitivity
• Reduce risk of dysglycemia (blood sugar highs and lows)
• Support pancreatic sensitivity & ability to produce adequate amounts of insulin
• Help prevent problems associated with out-of-control sugar levels (glycation) such as neuropathy, retinopathy, kidney damage, blood vessel damage, pancreatic damage.
• Prevent nutrient deficiencies induced by excessively high glucose/insulin levels
• Lower cardiovascular complications associated with diabetes and insulin resistance
• Protect from metabolic damage induced by excessive fructose consumption
• Lower homocysteine

Metabolic Synergy by Designs for Health Categories:

• Blood Sugar Support
• Endocrine Support
• Multivitamins/Vitamins

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Serving Size: 6 capsules

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Serving Size: 6 capsules.

Recommended Use: As a dietary supplement, take six capsules per day, two with each meal or as directed by your health care practitioner.

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Color, size or shape may appear different between lots.

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Melatonin | Designs for Health | 60 tablets

Melatonin is important in regulating sleep, circadian rhythm and the body’s natural time clock. It is also an important antioxidant, rapidly taken up by the brain, which acts as an effective scavenger of highly toxic free radicals, which induce DNA damage. Melatonin is a hormone produced by the pineal gland which serves to synchronize and coordinate biological functions of the body. This hormone appears in foods in only trace amounts and, therefore, supplementation supports the natural functioning of the pineal gland. The amount of melatonin produced by our bodies seems to decrease with age so supplementation may be ideal, especially for those over 50.

Melatonin deficiency may be defined based on quality of sleep and difficulty falling asleep, as well as specific urinary metabolites. By the age of 60, the body’s production may fall close to 50% of youthful levels. Due to its effects on sleep and many other metabolic functions, it is hypothesized that replacement that restores melatonin to youthful levels may have a multitude of benefits

Research shows that Melatonin may:

• increase life span and survival in animal studies
• improve sleep quality, especially during aging
• reduce jet lag or help adjust sleep times for shift workers
• relieve certain types of depression such as SAD (seasonal affective disorder)
• support Growth Hormone production
• stimulate the immune system
• increase antioxidant defenses
• be protective for the brain and improve recovery from stroke
• reduce migraines
• reduce side-effects from chemotherapy
• enhance the death of the cancer cells during chemotherapy while protecting healthy cells
• protect the liver against toxic injuries
• alleviate glaucoms
• reduce stress hormones
• reduce blood pressures

Melatonin by Designs for Health Categories:

• Endocrine Support
• Sleep Support

:: Sleep Problems ::
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Serving Size: 1 tablet.

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Serving Size: 1 tablet.

Recommended Use: As a dietary supplement, adults take one (1) tablet twenty (20) minutes before bedtime or, as directed by a health care practitioner.

Conditions For Which Melatonin is Not Recommended

• Autoimmune conditions such as Lupus or arthritis, because the immune stimulatory effect of melatonin may exacerbate the action of certain types of lympocytes or B-cells involved in the pathogenic course of these diseases
• Immune related cancers such as lymphoma and leukemia
• Pregnancy, lactation or during the time where fertility is desired

Interactions With Drug Therapy

Melatonin may not be suitable to administer along with MAO inhibitors and corticosteroid therapy.

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Not for use by children under 18 years. If pregnant or using a prescription drug, consult a health care practitioner. Do not take this product if you suffer from an autoimmune disease, depression, diabetes, endocrine disorder or thyroid condition. Do not use this product while operating a motorized vehicle or heavy machinery.

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Iodine Synergy | Designs for Health | 120 capsules

Iodine Synergy contains potassium iodide in a 10 mg therapeutic dose for supporting thyroid function, including healthy production of thyroid hormones, and the health of breast and prostate tissue. Typical supplementation range is 10-50 mg until normal iodine ranges are seen in testing. Potassium iodide is a weak salt and easily splits apart in the gut leaving free iodide ions to join together forming I2 Iodine, which is also needed by the breast and prostate for optimal health. The selenium in this product works synergistically with iodine to aid in conversion of T4 into T3, supply antioxidant protection of the thyroid gland, and research shows it is helpful for individuals with thyroid antibodies.

Selenium for thyroid health: Up to 40% of T4 is converted to T3 by peripheral organs such as the liver, kidney and spleen. Selenium is needed to convert T4 into T3. T3 is about ten times more active than T4. The 5’-deiodinase enzyme, involved in thyroid hormone conversion, is a selenoprotein dependent on the mineral selenium. Taking high doses of iodine long-term increases the need for selenium. Selenium levels are often low due to depletion by mercury.

Why do we need Iodine? Iodine deficiency can be a major contributor to the cause of congenital Hypothyroidism and goiter. Congenital hypothyroidism can lead to mental retardation, lower IQ and stunted growth. Symptoms typical of iodine. Deficiency include cold extremities, fatigue, insomnia, dry eyes, frequent crying (iodine is needed for lacromation and tearing), weight gain, cracking heels, and palpable tenderness in the sternum. Over the years, sodium restriction, as directed by many health professionals in an attempt to reduce hypertension and cardiovascular disease, has led to a decline in iodine intake. Many brands of salt today are not enriched with iodine. A goiter is often the result of the thyroid gland becoming enlarged in an effort to compensate for a lack of iodine. Currently, 200 million people are affected by goiters. Good sources of dietary iodine include iodized salt, seafood, kelp, seaweed, asparagus, spinach and Swiss chard. However, the body does not store iodine for long periods of time, so regular intake through diet, and possibly supplementation, is important.

The RDA for iodine may be too low: The RDA for iodine is only 150 mcg per day. The RDA for pregnancy is 175 mcg and for lactation 200 mcg iodine. These very low RDA’s were set as a minimum amount needed just to prevent hypothyroidism. Whole body needs and optimal thyroid function were not taken into account. Today as more and more doctors are testing for iodine deficiency, they are sometimes finding that a significant percentage of patients have suboptimal iodine intake and are not getting enough for optimal thyroid health.

Iodine for thyroid health: The thyroid is composed of spherical follicles that selectively absorb iodine (as iodide ions, I-) from the blood for production of thyroid hormones 25% of all the body’s iodide ions are in the thyroid gland.

Inside the follicles is a colloid which is rich in a protein called thyroglobulin. The colloidal material serves as a reservoir of materials for thyroid hormone production and, to a lesser extent, a reservoir of the hormones themselves. Thyroid hormones, thyroxine (T4) and triiodothyronine (T3), stimulate vital processes in every part of the body. These thyroid hormones have a major impact on the following functions:

• Growth
• Use of energy and oxygen
• Heat production
• Fertility
• The use of vitamins, proteins, carbohydrates, fats, electrolytes, and water
• Immune regulation in the intestine

Iodine is used in support of:

• Hypothyroidism
• Hyperthyroidism
• Hashimoto’s thyroiditis
• Fibrocystic breasts
• Goiter
• Breast cancer
• Thyroid nodules
• PCOS

Iodine for Breast and Prostate Health: Lack of iodine may be a contributor to fibrocystic breast disease. When researchers give rats an iodine blocking agent, sodium perchlorate, breast changes occur such as calcification and development of cysts that resemble human fibrocystic disease. Researchers have been able to produce breast cancer in animals by restricting iodine intake, as it appears iodine modulates the effect of estrogen on breast tissue. In the breast iodide stimulates production of lactoperoxidase which has functions other than attaching iodine to tyrosine. It regulates estrogen molecules outside the estrogen receptor on cells. Iodine slips into the cell by a different mechanism and induces apoptosis and cell division. Another good supplement to take, possibly in conjunction with iodine, to improve breast health is DIM•Avail. Iodine has a similar effect on prostate health as well.

Iodine concentrates in: stomach (helps make hydrochloric acid), breast, prostate and testes.

Iodide is found mainly in: thyroid, ovaries and breast tissue.

Iodine Synergy by Designs for Health Categories:

• Endocrine Support
• Female Health
• Minerals

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Serving Size: 1 capsule.

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Recommended Use: As a dietary supplement, take one capsule daily or as directed by your health care practitioner. All individuals on high-dose iodine should be managed by a qualified healthcare professional and should be monitored with objective laboratory evaluations during care.

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5 HTP Supreme | Designs for Health | 60 capsules

5 HTP Supreme by Designs for Health is a a higher dose 5HTP product with 100 mg per capsule as well as increasing the Pyridoxal-5-Phosphate (activated B-6) to 20 mg per capsule. 5-Hydroxytryptophan (5-HTP) is an amino acid that is the intermediate step between tryptophan and the important brain chemical serotonin. There is a massive amount of evidence that suggests that low serotonin levels are a common consequence of modern living.

The lifestyle and dietary practices of many people living in this stress-filled era results in lowered levels of serotonin within the brain. Our modern, stressful lives lower levels of the feel-good neurotransmitter serotonin. As a result, many people are overweight, crave sugar and other carbohydrates, experience bouts of depression, get frequent headaches, and have vague muscle aches and pain. All of these maladies are correctable by raising brain serotonin levels.

5 HTP is a Natural Way to Overcome Depression, Obesity, and Insomnia.

Certain aminos cause you to have better feeling of well being. Serotonin is a chemical that helps maintain a “happy feeling,” and seems to help keep our moods under control by helping with sleep, calming anxiety, and relieving depression. The brain also makes Dopamine, which makes people more talkative and excitable. It affects brain processes that control movement, emotional response, and ability to experience pleasure and pain. All of these chemicals are natural chemicals that affect our bodily processes.

Conditions associated with low serotonin levels helped by 5-HTP:

• Depression
• Obesity
• Carbohydrate craving
• Bulimia
• Insomnia
• Narcolepsy
• Sleep apnea
• Migraine headaches
• Tension headaches
• Chronic daily headaches
• Premenstrual syndrome
• Fibromyalgia

5 HTP Supreme by Designs for Health Categories:

• Amino Acid/Protein Formulas
• Endocrine Support
• Sleep Support
• Stress Management Support
• Weight Management

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Serving Size: 1 capsule

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Not recommneded for use by pregnant or lactating women, or if you are taking SSRIs or MAO inhibitors.

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Thyroid Synergy | Thyroid Function Support | Designs for Health 120 caps

Thyroid Synergy Designs for Health: Like all of our glands, the thyroid gland needs supportive nutrients from food or supplements to act as raw ingredient precursors for its proper function. Thyroid Stimulating Hormone needs to give the cells the message to synthesize Thyroxine. Thyroxine, known as T4, needs to be converted into active T3. Cortisol and insulin levels need to be controlled in order for this to happen successfully and precursors and coenzymes must be available. Thyroid Synergy is here!

Thyroid Synergy is a formulary, encapsulated product designed to be an all-in-one thyroid support product. In just one product, it is now possible to have botanical and nutritional enhancement of thyroid hormone production, peripheral conversion of T4 to T3, as well as receptor function and recognition of thyroid hormones. The non-stimulating adaptogenic botanical American ginseng (Panax quinquifolius) has been added to Thyroid Synergy to help control variations in cortisol, which can have profound effects on peripheral thyroid hormone conversion, as well as serum blood glucose and insulin levels, inducing dysglycemia and laying the foundation for metabolic syndrome.

Thyroid Synergy Designs for Health Contains Supportive Herbs: American GinsengRoot, ColeusForskohli (Forslean®) The non-stimulating adaptogenic botanical American ginseng (Panex quinquifolius) helps control variations in cortisol, which can have profound deleterious effects on peripheral thyroid hormone conversion, as well as serum blood glucose and insulin levels, inducing dysglycemia and laying the foundation for metabolic syndrome.

Why is ColeusForskohli Extract Necessary For Thyroid Support? Coleus forskohlii is necessary for several reasons. Its active constituent forskohlin is a diterpene from the roots of Coleus forskohli, known to directly activate the adenylate cyclase enzyme and raise cyclic AMP levels in many tissues. This is important because Thyroid Stimulating Hormone (TSH) stimulates all steps in the synthesis and secretion of T3 and T4. The first step is the binding of TSH hormone to TSH receptors located on the basal membrane of thyroid epithelial cells, followed by elevation of cyclic AMP levels, and a subsequent cascade of phosphorylation reactions via activation of protein kinase A. The final step is the secretion of thyroid hormones T4 and T3 which again couldn’t happen without cAMP. Hypothyroid patients need support in the area of fat metabolism. Coleus is known to reduce adipose assimilation and increase the lipolysis of fats. Coleus aids in the following functions:

• inhibiting the synthesis of adipose tissue
• increasing response to lipolytic hormones which are produced in less quantity as we age
• utilizing stored fat. It may also play a role in aiding the production of digestive enzymes and supporting the immune system, both being helpful for hypothyroid patients.

Thyroid Synergy also contains Copper and Coleus Forskohli Cyclic AMP and copper, as well as Tyrosine, are involved also in the production of “feel good” catecholamines such as dop-amine and norepinephrine. This could be very helpful since hypothyroid patients are so susceptible to depression. Cyclic AMP is also a key player in regulating steroid hormone synthesis. These hormones include estrogen, progesterone and testosterone and depend on cholesterol for their making. Women with hypothyroidism can have very severe PMS.

Chromium, Zinc and Manganese are also in Thyroid Synergy: These minerals are needed for thyroid support to help control insulin since insulin blocks phosphorylation and therefore opposes the action of epinephrine and can impede thyroid hormone production. Chromium also helps to control cholesterol levels that often elevate in hypothyroid patients as well as control blood sugar levels which are challenged by poor adrenal and thyroid gland health.

N-Acetyl L-Tyrosine and Iodine in Thyroid Synergy: Tyrosine and iodine are intimately involved in the synthesis of Thyroxine. N-Acetyl L-Tyrosine is much more stable and better absorbed than L-Tyrosine. Vitamin B2 supports these enzymatic conversions. A lack of iodine is a known contributing cause of goiter. Potassium iodide has been shown to protect the thyroid gland from radiation damage. Potassium levels are often low in patients with poor thyroid and poor adrenal function. Potassium is necessary for getting thyroid hormone into our cells and is very energizing.

Thyroid Synergy Contains Selenium: Which is a key cofactor in the enzymatic conversion (ID-I enzyme) of T4, thyroxine hormone, to the more active T3, triiodothyronine. Selenium also protects the thyroid gland from mercury damage and from free radical damage caused by chemicals and heavy metals. Selenium helps to make the powerfully protective enzyme glutathione peroxidase. A study looked at how selenium deficiency affected ID-I enzyme (I iodothyronine 5′-deiodinase) levels in the body. Selenium deficient rats had the following results:

• Hepatic and renal ID-I activities decreased by 60% and 50% respec¬tively, serum levels of T3 reduced 36%, and T4 increased by 32%.
• GSH-Px (glutathione peroxidase) activities in the whole blood and liver decreased by 61% and 82% respectively. LPO (lipid peroxide) concentrations in serum and liver increased by 53% and 40% respectively. The results of a Graves’ disease study clearly indicated that supplementa-tion with antioxidants in the treatment of Graves’ disease is justified, particularly those containing selenium.

Vitamin A, Zinc and Selenium: Studies tell us that TTR (Transthyretin) an extracellular transfer protein in humans is responsible for binding both T4 and T3 with a preference for T4. This protein also binds vitamin A known to be important for Thyroid function. TTR is an extra cellular transport protein involved in the distribution of thyroid hormones and vitamin A. Hypothyroid patients often have a yellow-orange coloring to their skin because of very poor conversion of beta-carotene into vitamin A. Zinc is needed for this conversion. Significantly lower levels of zinc and selenium are found in the thyroids of patients with thyroid cancer compared to other thyroid patients. Zinc is likely as potent a thyroid antioxidant as selenium is. Both of these minerals protect against heavy metals.

Can Selenium Supplementation Help Thyroiditis?

Thyroiditis is inflammation of the thyroid gland. The most common type is autoimmune thyroiditis, in which, for complicated reasons, the body attacks the thyroid gland, decreasing its production of thyroid hormones. Selenium appears to have two essential functions related to thyroid health. First, it is a component of the detoxifying enzyme glutathione peroxidase. If selenium is unavailable, this enzyme does not work as effectively. Since glutathione peroxi¬dase helps to quench free radicals, lowered activity may result in increased free-radical generation and increased damage to an already inflamed thyroid gland. Second, selenium is a key cofactor in the enzymatic conversion of thyroid hormone thyroxine (T4) to the more active triiodothyronine (T3) making selenium important for healthy thyroid function. In two recent studies, researchers tested this idea by giving subjects T4 with or without selenium supplements. In both studies the combined supplementation of T4 and selenium, compared with T4 only, was beneficial in decreasing the autoimmune-induced inflammation as measured by antibod¬ies against thyroid peroxidase, particularly in those with very high antibody levels. These two studies do show selenium is helpful and well-tolerated at the dose of 200 mcg daily.

Thyroid Synergy by Designs for Health Categories:

• Endocrine Support
• Female Health
• Herbal Products
• Mitochondrial Support & Energizers
• Weight Management

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How Do I Use Thryoid Synergy? Recommended Use:  As a dietary supplement, take two capsules per day with meals or as directed by your health care practitioner.

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Adrenal Complex | Designs for Health 120 caps

Adrenal Complex by Designs for Health’s new Adrenal Complex now more than ever meets the needs of those looking for a glandular-based adrenal product, as it offers a more comprehensive support for overall adrenal and HPA axis function. This is an ideal product for individuals with extreme adrenal bunout! N-acetyl L-tyrosine and vitamin C were added in order to provide critical catecholamine repletion, often necessary for those experiencing chronic stress.

Adrenal Complex was designed with the intention of rejuvenating tired adrenal glands. With ever increasing concerns over the safety of glandular materials, Designs for Health has reexamined this issue and has gone to extreme lengths to obtain the purest and cleanest sources of glandulars on the market today. Adrenal Complex’s glandular materials are obtained only from certified BSE-free countries (typically Argentina) and are freeze dried to avoid rancidity. The B-vitamin profile of the product was rounded out to include a more complete spectrum of B’s most of which are provided in their pre-activated phosphorylated form. Also has been known to help hair growth! Adrenal fatigue can wreak havoc with your life. In the more serious cases, the activity of the adrenal glands is so diminished that you may have difficulty getting out of bed for more than a few hours per day. With each increment of reduction in adrenal function, every organ and system in your body is more profoundly affected. Changes occur in your carbohydrate, protein and fat metabolism, fluid and electrolyte balance, heart and cardiovascular system, and even sex drive.

Adrenal Complex by Designs for Health Categories:

• Endocrine Support
• Mitochondrial Support & Energizers
• Stress Management

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Recommended Use: As a dietary supplement, take two capsules per day with meals or as directed by your health care practitioner.

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Consult with your health care practitioner before use if you are pregnant or lactating or if you are on prescription medication, especially sulfa drugs

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